Indiana University School of Medicine
Principal Investigators: Kara Wools-Kaloustian and Constantin Yiannoutsos
Co-Investigators: John M. Humphrey and Suzanne Goodrich
Regional Data Manager:Beverly Musick
Biostatisticians: Constantin Yiannoutsos and Giorgos Bakoyannis
Indiana University School of Medicine (IUSM) serves as the East African IeDEA Regional Data & Coordinating Center (RDC) in the United States. It provides overall coordination for the East African Consortium including project development, data management and statistical analysis support. In addition, the site provides mentoring and practical support to site investigators, data managers and biostatisticians at East Africa IeDEA sites. The IUSM RDC serves as the interface between the East African IeDEA Consortium and with external partners including the six other IeDEA Regions.
Brown University/Miriam Hospital, Providence, RI
Site Principal Investigator: Rami Kantor
Brown University/Miriam Hospital will provide laboratory expertise for IeDEA in the areas of sample collection, handling and testing and data analysis of HIV drug resistance in the Adolescent Care Cascade.
Columbia University Mailman School of Public Health
Site Principal Investigator: Batya Elul
The Columbia University is participating in analyses using IeDEA East Africa data, with a particular focus on evaluation of outcomes among adolescents, and examination of site and program level determinants of key patient outcomes across the HIV care cascade.
Duke University School of Medicine
Site Principal Investigator: Neelima Navuluri
The Division of Pulmonary, Allergy and Critical Care Medicine at the Duke University School of Medicine collaborates on the Tuberculosis Sentinel Research Network (TB-SRN) project to examine the immediate and long-term outcomes of people diagnosed with tuberculosis (TB), with a focus on identifying and addressing factors associated with post-tuberculosis lung disease.
Mt. Sinai, New York
Site Principal Investigator: Rachel Vreeman
The Arnhold Institute for Global Health at Icahn School of Medicine at Mount Sinai provides East Africa and Global IeDEA with leadership in Pediatric and Adolescent HIV Research. This group coordinates the development and conduct of pediatric and adolescent research projects, with a focus on evaluating and improving long-term outcomes of pediatric HIV and maintaining a cohort of adolescents living with HIV.
University of California, San Francisco (UCSF)
Site Principal Investigator: Jeffrey Martin (Uganda) and Craig Cohen (Kenya)
Site Co-investigators: David Glidden, Jayne Kulzer
University of California, San Francisco has a prominent role in collaboration with IeDEA field sites in Mbarara, Uganda, through the Immune Suppression Syndrome (ISS) clinic at the Mbarara Regional Referral Hospital, the Infectious Diseases Institute (IDI) in Kampala, Uganda as well as through the Fostering Advances in Care, Education and Science (FACES) program in Kisumu County in Kenya. In addition, UCSF supports the EA-IeDEA collaboration with regional and global collaborations and capacity building of early-stage investigators in East Africa through a variety of training programs such as the GloCal Health Fellowship.
In Uganda, as part of IeDEA, the UCSF collaboration with IDI and ISS provides leadership in analyses and projects related to Kaposi’s Sarcoma as well as the impact of the provider and health care environment on patient outcomes. Investigators from UCSF also provide leadership in analyses addressing cervical cancer and other women’s health issues.
In Kenya, FACES, a UCSF and Kenya Medical Research Institute (KEMRI) collaboration, builds on its long-standing partnership with the local Ministries of Health (MOH) in HIV service delivery and research. FACES engagement with IeDEA involves provision of HIV-related clinical data from two high volume health facilities in Kisumu County and analysis and projects focused on adolescent retention in care, tuberculosis (TB) treatment outcomes, and formative work on telemedicine.
University of Washington
Site Principal Investigator: Rena Patel
The Division of Allergy & Infectious Diseases, University of Washington (UW) will co-lead the MANGO multi-regional project for IeDEA by providing overall guidance on study design, implementation, analysis, interpretation of findings, and support operationalization of the study aims with IeDEA.